International Journal of Medical Science and Clinical Invention http://valleyinternational.net/index.php/ijmsci <p>Welcome to the International Journal of Medical Science and Clinical Invention (IJMSCI). Our journal is dedicated to publishing cutting-edge research and innovative clinical advancements in the field of medical science.</p> <p>Our mission is to serve as a platform for researchers, clinicians, and healthcare professionals to disseminate their findings and share their expertise with the global community. IJMSCI provides a wide-ranging and interdisciplinary forum for the exchange of ideas and information in the areas of medical science, clinical practice, and invention.</p> <p>We publish original research articles, review articles, case reports, and short communications in all areas of medical science and clinical invention, including but not limited to, internal medicine, surgery, pediatrics, obstetrics and gynecology, dermatology, orthopedics, neurology, and oncology.</p> <p>At IJMSCI, we strive to maintain the highest standards of quality and rigor in our publishing process. Our editorial board comprises experts from leading medical institutions worldwide, and our peer-review process ensures that only the most relevant, novel, and impactful research is published.</p> <p>We welcome submissions from researchers and clinicians around the world and encourage you to share your work with us. If you have any questions or need assistance, our editorial team is here to help.</p> <p>Join the global community of medical science and clinical invention experts and stay ahead of the curve with IJMSCI!</p> Valley International Journals en-US International Journal of Medical Science and Clinical Invention 2348-991X A rare case of Vieussens ring fistula to pulmonary artery finding on cardiac magnetic resonance: A Case report and Literature Analysis. http://valleyinternational.net/index.php/ijmsci/article/view/4782 <p>A 61-year-old woman presents with functional decline due to dyspnea and angina. Cardiac Magnetic Resonance imaging reveals a Vieussens' arterial ring (VAR) with a fistula from the coronary artery to the main pulmonary artery trunk.</p> Alexanderson-Rosas E Franco-Rodríguez KY Claudio-Moreno DS Díaz-Cervantes MA León-Laredo RA Chávez-Vázquez LF Rodríguez-García LA Cano-Zárate R Meave-González A Copyright (c) 2024 International Journal of Medical Science and Clinical Invention https://creativecommons.org/licenses/by/4.0/ 2024-08-13 2024-08-13 11 08 7223 7225 10.18535/ijmsci/v11i8.01 Algorithm for Prevention of Recurrent Pregnancy Loss and Adverse Pregnancy Outcomes in Patient with Inherited Thrombophilia http://valleyinternational.net/index.php/ijmsci/article/view/4784 <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Pregnancy-related complications such as recurrent pregnancy loss, recurrent implantation failure, preeclampsia, intrauterine fetal growth restriction, and gestational diabetes pose significant risks to both maternal and fetal health. Emerging evidence suggests that genetic variations may contribute to the etiology of many of these conditions.</p> <p>Understanding the interplay between genetic mutations and pregnancy complications can enhance risk assessment and enable personalized medical management for affected individuals. Further research is needed to better elucidate these relationships and guide clinical decision-making.</p> <p>The objective of this study is to emphasize the medical implications of detecting congenital abnormalities in pregnant women and to underscore the importance of risk prediction, early diagnosis, and personalized care in improving maternal and fetal health outcomes. This comprehensive analysis underlines the critical role of algorithms in preventing severe pregnancy-related complications and enhancing targeted interventions in obstetric care. By elucidating the intricate pathogenesis of these conditions, the study provides valuable insights for improving specific therapeutic approaches.</p> Zlatko Kirovakov Emiliana Konova Nadezhda Hinkova Stefani Markova Copyright (c) 2024 International Journal of Medical Science and Clinical Invention https://creativecommons.org/licenses/by/4.0/ 2024-08-21 2024-08-21 11 08 7226 7235 10.18535/ijmsci/v11i8.02 Acute Neurological disorders in pregnancy and postpartum period – Systematic review http://valleyinternational.net/index.php/ijmsci/article/view/4785 <p><strong>Objective:</strong> Stroke among young and elderly people is frequently caused by cervical artery dissection (CeAD). A rupture in any one or more blood vessel layers of tissue results in cervical artery detachment. Information for the causative factor of one-fifth of ischemic stroke patients is available from case reports and case reviews. CeAD is rare during pregnancy and in the early postpartum period. In addition, other risk factors have been suggested, such as infection, migraine, hyperhomocysteinaemia, and the 677TT genotype of the 5,10-methylenetetrahydrofolate reductase gene (<em>MTHFR</em>&nbsp;677TT).</p> <p><strong>Limitation: </strong>A lack of neurological diseases during pregnancy and the postpartum period provides major obstacles for both the mother and child. The restricted therapeutic choices might impair care and complicate management. Multidisciplinary care is frequently required to achieve a delicate equilibrium between the health of the mother and the risk of foetal hazards.</p> <p><strong>Method:</strong> This systematic review with a systematically registered protocol was the strategy to study the clinical presentation, management, and outcome of this situation. For inclusion, 40 studies were found through language-free searches on Google Scholar and PubМed.</p> <p><strong>Results:</strong> The key factors of the greatest incidence found were migraine, hyperlipidemia, connective tissue diseases, HELLP syndrome, preeclampsia or eclampsia, and the protracted second phase of labor. The most frequent complaint was a headache with soreness in the neck. Anticoagulant medication, anti-platelet agents, and endovascular procedures were among the acute medical interventions.</p> <p><strong>Conclusion:</strong> This research emphasizes the value of efficient, all-encompassing care and raised knowledge to optimize results in pregnant women.</p> Zlatko Kirovakov Nadezhda Hinkova Antonio Dushepeev Svetoslav Todorov Copyright (c) 2024 International Journal of Medical Science and Clinical Invention https://creativecommons.org/licenses/by/4.0/ 2024-08-21 2024-08-21 11 08 7236 7248 10.18535/ijmsci/v11i8.03