TY - JOUR AU - Ganouni3 , Rhizlane Belbaraka1, Jamal Drissi1 , El Moukhtar Eroui1 , Hanane Rais2 , Najat Cherif Idrissi El AU - Mouna Khouchani1, Abdelhamid Elomrani1 , PY - 2017/07/12 Y2 - 2024/03/29 TI - The Largest Malignant Pheochromocytoma: A Case Report and Literature Review JF - International Journal of Medical Science and Clinical Invention JA - ijmsci VL - 4 IS - 7 SE - Articles DO - 10.18535/ijmsci/v4i7.09 UR - https://valleyinternational.net/index.php/ijmsci/article/view/895 SP - AB - <p>: Introduction: Malignant pheochromocytoma is a rare neuroendocrine tumor with an annual incidence of 3–8 cases per 1 million per year in the general population. Its clinical presentation can vary greatly. There are few published cases of giant pheochromocytomas. We report a case of the largest tumor in the world. The literature is reviewed to evaluate the spectrum of disease presentations and the available options for disease management and treatment. Case presentation: A 52-year-old male, originally from El Kelaa des Sraghna in the middle of Morocco, which had a 36cm mass of the left suprarenal gland with metastatic lesions. He was treated with a combination chemotherapy regimen of cyclophosphamide, vincristine and dacarbazine. Conclusion: A heterogeneous clinical presentation of malignant pheochromocytoma and a short response to chemotherapy had been observed in our case. However, controlled studies need to determine a standard of care.</p> ER -