International Journal of Medical Science and Clinical invention <p><strong>International Journal of Medical Science and Clinical invention</strong>&nbsp;is an international, peer-reviewed journal that welcomes original research articles and reviews on&nbsp;current advances in Medical sciences,&nbsp;preclinical&nbsp;and&nbsp;clinical medicine, and&nbsp;related disciplines.</p> <p>The Journal’s primary aim is to make every effort to contribute to progress in medical sciences. The strive is to bridge laboratory and clinical settings with cutting edge research findings and new developments.</p> <p><em>International Journal of Medical Science and Clinical invention&nbsp;</em>&nbsp;publishes articles which bring novel insights into&nbsp;diagnostic and molecular imaging, offering essential prior knowledge for diagnosis and treatment indispensable in all areas of medical sciences. It also publishes articles on&nbsp;<strong>Clinical</strong>&nbsp;pathological sciences&nbsp;giving foundation knowledge on the overall study of human diseases. Through its publications&nbsp;<em>International Journal of Medical Science and Clinical invention</em>&nbsp;also stresses the importance of&nbsp;Medical sciences&nbsp;as a rapidly and ever expanding area of research on drug design, development, action and evaluation contributing significantly to a variety of scientific disciplines.</p> Valley International Journals en-US International Journal of Medical Science and Clinical invention 2454-9576 Factors related to smoking behavior of students in Traditional Pesantren Aceh Besar, Indonersian in 2018 <p>Smoking is a serious issue causing a variety of adverse health effects. However, pesantrens (Islamic boarding schools) do not prohibit smoking, their leaders and teachers also smoke, and cigarettes are sold freely outside. The students have further admitted that anyone may smoke any where and that no socialization on smoking has ever been conducted in pesantrens.The purpose of this study was to analyze the relationships between the student smoking behavior, knowledge, and attitudes towards the social marketing mix in traditional pesantrens.This study employed a descriptive analytics with the cross sectional study design<em>.</em>The total sample was 162 students from a pesantren in Aceh Besar, Indonesia<em>.</em>The results showed that there were significant relationships between student smoking behavior and age <strong>(</strong><em>p-value </em><em>= </em>0.031<strong>)</strong>, and parents’ smoking behavior (<em>p-value</em><em>= </em>0<em>.</em>003), and peersmoking behavior (<em>p-value </em><em>=</em>0.000), and knowledge of the social marketing mix (<em>p-value</em><em>= </em>0.010), and attitudes (<em>p-value </em><em>= </em>0.000) towards the social marketing mix. It is thus recommended tha tall parties develop a pesantren as one of the focus areas of smoking prevention activities</p> Ismail . Teuku Tahlil Nurussalam . dan Zurnila Marli Kesuma Copyright (c) 2019 International Journal of Medical Science and Clinical invention 2019-06-28 2019-06-28 6 06 4495 4500 10.18535/ijmsci/v6i6.02 Assessment of Treatment Response in Collagen Vascular Disease Associated Interstitial Lung Disease with Combination of Prednisolone and Azathioprine <p><strong>Background: </strong>Collagen vascular diseases are a heterogenous group of autoimmune disorders of unknown etiology of which ILD is the most common pulmonary complication. Treatment is usually aimed at slowing or preventing progression rather than in the hope of a striking short-term response.</p> <p><strong>Materials and Methods: </strong>The aim of the study is to assess response to treatment&nbsp;&nbsp; in patients with collagen vascular disease associated Interstitial lung disease who were started on combination of Azathioprine and Prednisolone.</p> <p><strong>Results: </strong>Majority of patients remained stable following 6 months of treatment.</p> <p>Improvement in FVC in millilitres showed a trend towards significant difference between UIP and NSIP patterns of ILD.</p> <p><strong>Conclusion:</strong>Treatment response in collagen vascular disease associated ILD is largely dependent on the type of underlying lung disease.</p> Dr. Hemalatha V S Dr. K. Anitha Kumari Copyright (c) 2019 International Journal of Medical Science and Clinical invention 2019-06-21 2019-06-21 6 06 4501 4504 10.18535/ijmsci/v6i6.03 Effect of intraoperative radiotherapy on wound healing in breast cancer patient post breast conserving surgery, KSUMC, Riyadh, Saudi Arabia: Case series and review of literature. <p>Intraoperative radiotherapy during breast-conserving surgery is being studied as an alternative to 6 weeks of external beam radiotherapy (EBRT) for low-risk women; it can be delivered using electrons (intraoperative electron radiotherapy, IOERT) or 50-kV X-rays. Intraoperative radiation therapy (IORT) may pose a risk for wound complications. &nbsp;Between March 2018 and June 2018, 5 breast cancer patients, all eligible for breast conserving surgery (BCS), were treated at the King Saud Medical city with IORT using the IOERT. Complete data sets for age, stage (T, N, and M), and histology and hormone receptor status were available in 5 cases. Parameters to identify eligible patients are as follows: ESTRO: &gt;50 years, invasive ductal carcinoma/other favourable histology (IDC), T1-2 (≤3 cm), N0, any hormone receptor status, M0; ASTRO: ≥60 years, IDC, T1, N0, positive estrogen hormone receptor status, M0; TARGIT E “elderly”, risk adapted radiotherapy with IORT followed by external beam radiotherapy in case of risk factors in final histopathology. Consecutive patients operated on with the same surgical technique and given IORT were included. Wound complications were evaluated.</p> Dr. Maha Alamodi Alghamdi Abdulaziz Saleh Altwjri Abdullah Alsuhaibani Abdulaziz Alsaif Copyright (c) 2019 International Journal of Medical Science and Clinical invention 2019-06-30 2019-06-30 6 06 4505 4510 10.18535/ijmsci/v6i6.04 A New Dıagnosıs Klınefelter Syndrome Refer To Hospital With Dyspeptic Complaınts <p>Klinefelter Syndrome is the most common sex chromosomal disorder in males. The clinical features of Klinefelter syndrome are characterized by significant testicular dysfunction, hypogonadal symptoms, atrophic testes and gynecomastia . These patients can apply to the physician with symptoms specific to the syndrome or general symptoms. In addition to specific physical examination findings, the hormone profile is consistent with primary hypogonadism. The definitive diagnosis is made by karyotype analysis of peripheral blood lymphocytes. Early diagnosis and treatment are important. With hormone replacement therapy, muscle mass, bone mineral density and libido are improved. In general, patients with Klinefelter Syndrome are infertile, but fertilization can be achieved with assisted reproductive techniques. We present a case with dyspeptic symptoms and suspected physical examination findings and diagnosed as Klinefelter Syndrome.</p> Hatice Beyazal Polat Aydın Demirbaş Teslime Ayaz Sibel Demirbaş Copyright (c) 2019 International Journal of Medical Science and Clinical invention 2019-06-29 2019-06-29 6 06 4511 4512 10.18535/ijmsci/v6i6.05