International Journal of Medical Science and Clinical invention https://valleyinternational.net/index.php/ijmsci <p><strong>International Journal of Medical Science and Clinical invention</strong>&nbsp;is an international, peer-reviewed journal that welcomes original research articles and reviews on&nbsp;current advances in Medical sciences,&nbsp;preclinical&nbsp;and&nbsp;clinical medicine, and&nbsp;related disciplines.</p> <p>The Journal’s primary aim is to make every effort to contribute to progress in medical sciences. The strive is to bridge laboratory and clinical settings with cutting edge research findings and new developments.</p> <p><em>International Journal of Medical Science and Clinical invention&nbsp;</em>&nbsp;publishes articles which bring novel insights into&nbsp;diagnostic and molecular imaging, offering essential prior knowledge for diagnosis and treatment indispensable in all areas of medical sciences. It also publishes articles on&nbsp;<strong>Clinical</strong>&nbsp;pathological sciences&nbsp;giving foundation knowledge on the overall study of human diseases. Through its publications&nbsp;<em>International Journal of Medical Science and Clinical invention</em>&nbsp;also stresses the importance of&nbsp;Medical sciences&nbsp;as a rapidly and ever expanding area of research on drug design, development, action and evaluation contributing significantly to a variety of scientific disciplines.</p> Valley International Journals en-US International Journal of Medical Science and Clinical invention 2454-9576 Comparison of the functional food knowledge-awareness levels and consumption frequencies of university students https://valleyinternational.net/index.php/ijmsci/article/view/2235 <p><strong>Aim:</strong> The increase in the level of education brings with it many behavioral changes such as healthy nutrition in food purchasing behavior, flexibility against new products. The aim of this study is to create a perspective on whether nutrition and dietetics students' knowledge and awareness levels and functional frequencies are changed with theoretical knowledge.</p> <p><strong>Material and Method:</strong> The study consists of 1st and 4th year students in Nutrition and Dietetics Department studying in Private University. The number of students willing to participate voluntarily is 99. 55 (55.6%) of the students were in the 1st grade and 44 (44.4%) were in the 4th grade. The questionnaire used in the study was composed of parts such as demographic characteristics of the students and questions about functional food, functional food sections and the section on measuring the consumption frequency, judgments about functional foods, opinions about whether to prefer functional foods.</p> <p><strong>Results: </strong>When the study is examined according to educational level, 16,4% of 1st year students and 77.3% of 4th grade students have previously heard and are familiar with the term functional food. &nbsp;In this case, the rate of hearing the term functional food of 4th grade students was found to be statistically significantly higher than the first year students who have not yet received sufficient academic education. When the percentages of the 1st grade students were not aware of the functional foods and they did not know enough about the function of the product, the rate of not choosing was significantly higher than the 4th grade students.</p> Hülya Demir Başak Karakaya Copyright (c) 2019 International Journal of Medical Science and Clinical invention http://creativecommons.org/licenses/by-nc-sa/4.0 2019-08-04 2019-08-04 6 08 4530 4538 10.18535/ijmsci/v6i8.01 Associations between Prognostic Factors Determining the Survival of Thyroid Papillary Carcinoma Patients https://valleyinternational.net/index.php/ijmsci/article/view/2248 <p>Several systems enabling the evaluation of prognosis for patients with differentiated thyroid cancers include, together with some other clinical variables, such ones as patient’s tumor size and age. Associations between these prognostic factors are not yet completely understood; that is why the aim of this investigation was to study the frequency of thyroid papillary carcinoma spreading with different tumor aggressive characteristics depending on patient sex and age as well as on primary neoplasm size. All these three factors are significant for the disease prognosis, their impact being, however, not the same. The results suggest the tumor size as well as patient age and sex to be also essential and to impact on the spreading of tumor characters determining their aggressiveness. The effect of the tumor size differs in patients of different sex and age.</p> Guda B.B. Copyright (c) 2019 International Journal of Medical Science and Clinical invention http://creativecommons.org/licenses/by-nc-sa/4.0 2019-08-05 2019-08-05 6 08 4539 4543 10.18535/ijmsci/v6i8.02 Stem cells and mesenchymal stem cell markers https://valleyinternational.net/index.php/ijmsci/article/view/2255 <p>Stem cells are undifferentiated cell type characterized by colonogenic ability, self-renewal and multi-lineage differentiation. They are classified into the following categories: embryonic stem cells [ESC], somatic stem cells [or adult stem cells] and induced pluripotent stem cells [iPSC]. Stem cells represent area of interest for wide range of scientists, as they are promising tool for regenerative therapy. Their differentiation ability is significantly affected by various factors of the local environment. Additional research will provide more information about the optimal cell culture conditions when stem cells are cultivated for clinical purpose, to avoid side effects like uncontrolled cell proliferation and premature differentiation.</p> Zornitsa Mihaylova Copyright (c) 2019 International Journal of Medical Science and Clinical invention http://creativecommons.org/licenses/by-nc-sa/4.0 2019-08-06 2019-08-06 6 08 4544 4547 10.18535/ijmsci/v6i8.03 Neurological Differences and Pharmaceuticals in Persons with Autism https://valleyinternational.net/index.php/ijmsci/article/view/2276 <p>Given the rise of persons diagnosed with autism, this paper is to highlight psychopharmacueticals that are often used in the treatment of autism symptomology.&nbsp; I begin with a brief summary of autism followed by a summation of biological differences. A discussion of pharmaceuticals often used to alleviate the symptoms associated with autism is also discussed. Lastly, a brief conclusory statement is provided.</p> Gwendolyn Barnhart Copyright (c) 2019 International Journal of Medical Science and Clinical invention http://creativecommons.org/licenses/by-nc-sa/4.0 2019-08-29 2019-08-29 6 08 4548 4550 10.18535/ijmsci/v6i8.04 A Study of Vitamin D Deficiency in Patients of Epilepsy on Anti-Epileptic Drug https://valleyinternational.net/index.php/ijmsci/article/view/2190 <p>Medical literature has recently focused attention on the impact of vitamin D on various aspects of health. Besides its pivotal role in calcium homeostasis and bone mineral metabolism, it is now recognized to serve&nbsp; a wide range of fundamental biological functions. The association between vitamin D, antiepileptic drugs , and bone health in individuals with epilepsy has been recognized for more than 30 years . Seizures themselves pose a risk for injury, including fractures; and the added co-morbidity of poor bone health increase this risk, especially in children with who suffer from seizures with motor manifestations, as well as those with impaired motor function and coordination. Many AEDs are inducers of hepatic cytochrome P450 metabolism. It has been postulated that these AEDs result in increased hepatic metabolism of vitamin D, leading to low vitamin D levels. However, non-enzyme inducing AEDs have also been associated with low vitamin D levels and in turn with poor bone health. Therefore, although the newer AEDs are less-potent enzyme inducers than older AED, they are not necessarily inert in bone metabolism. Studies have reported variable changes in vitamin D levels in children taking AEDs. We aimed to describe the prevalence of and risk factors for vitamin D deficiency among children with epilepsy on antiepileptic drugs.</p> Dr. Anuya Chauhan mam Dr.Gargi Pathak mam Dr.Devhuti Godhani Copyright (c) 2019 International Journal of Medical Science and Clinical invention http://creativecommons.org/licenses/by-nc-sa/4.0 2019-08-09 2019-08-09 6 08 4551 4553 10.18535/ijmsci/v6i8.05 Haematological Profile of Hiv Patients In Relation to Immune Status in Kumasi, A Case Study. https://valleyinternational.net/index.php/ijmsci/article/view/2178 <p><strong>Introduction:</strong> Human immunodeficiency virus (HIV) infection represents the most common cause of acquired immune deficiency leading to AIDS. CD4 is found on immune cells like T cells, macrophages and monocyte. HIV infects CD4 cells and in the absence of suitable therapy leads to CD4 cell lymphopenia. The progressive decline in CD4 cells eventually leads to the development of haematological abnormalities, opportunistic infections, wasting, cancer and death.</p> <p><strong>Aim</strong>: The study compared the haematological profiles to the CD4 count among HIV patients attending ART at Komfo Anokye Teaching Hospital and Obuasi Government Hospital.</p> <p><strong>Materials and Method</strong>: a cross sectional analytical study involving 385 selected patients with HIV in Ashanti Region was done. CD4 count and Full blood count were performed to determine the immune status of the patients and haematological parameters<strong>. </strong></p> <p><strong>Results:</strong> Out of 385 HIV patients enrolled in the study, the mean age, weight, and duration of therapy was 40.62 years old, 58.33 kg, and 6.17 years respectively. A higher proportion of the study participants were females (73.7%), married (42.7%), had HIV-1 (97.7%) and informal education (83.0%). CD4 count was directly associated with haemoglobin levels (r=0.32), WBC count (r= 0.23) especially with neutrophils. However, CD4 count was negatively associated with lymphocyte count (r= -0.14).</p> <p><strong>Conclusion</strong>: This study revealed that there is a strong association between CD4 counts and the severity of anemia and neutropenia in HIV/AIDS patients. Anemia and neutropenia in HIV patients can be considered as good clinical indicators to predict and access the underlying immune status.&nbsp;&nbsp;&nbsp;</p> <p>KEY WORDS: HIV/AIDS, CD4 count, neutropenia,</p> David Ntiamoah Ofosu Yeboah Marfo- Debrekyei Joana Duah Lilian Donkor Eddie-Wiiliams Owiredu Copyright (c) 2019 International Journal of Medical Science and Clinical invention http://creativecommons.org/licenses/by-nc-sa/4.0 2019-08-10 2019-08-10 6 08 4554 4558 10.18535/ijmsci/v6i8.06 Sjögren's syndrome-literature review and clinical case presentation https://valleyinternational.net/index.php/ijmsci/article/view/2278 <p>Sjögren's syndrome (SS) is a systemic disorder with clinical presentation of dry eyes, dry mouth and autoimmune disorder. Recently the number of patients with SS is increasing. In middle age female patients, having symptoms of dry mouth and salivary glands enlargement, SS should always be suspected. We present a&nbsp; clinical case report of a patient with SS. Based on the therapy and&nbsp; long term follow-up, we may conclude that via appropriate treatment significant improvement could be achieved.</p> Zornitsa Mihaylova Pavel Stanimirov Copyright (c) 2019 International Journal of Medical Science and Clinical invention http://creativecommons.org/licenses/by-nc-sa/4.0 2019-08-24 2019-08-24 6 08 4559 4561 10.18535/ijmsci/v6i8.07 Benign Symmetrical Lipomatosis (Bsl) Of The Head And Neck: Clinical Case Presentation https://valleyinternational.net/index.php/ijmsci/article/view/2261 <p>Benign symmetrical lipomatosis (BSL) is a rare pathological finding with an alcohol connection. It predominantly affects males in the age between 30 and 60-year-old. Once developed, the disease does not undergo regression. The fatty accumulations have constant and progressive overgrowth that may significantly affect breathing, eating and speech. The most effective method for treatment is the surgical removal of the tumor masses.&nbsp; In the following we present a clinical case report of a 44-year-old male with BSL.</p> Pavel Stanimirov Samuil Dzhenkov Copyright (c) 2019 International Journal of Medical Science and Clinical invention http://creativecommons.org/licenses/by-nc-sa/4.0 2019-08-24 2019-08-24 6 08 4562 4564 10.18535/ijmsci/v6i8.08