International Journal of Medical Science and Clinical Invention

Gastrointestinal Norovirus Infections at the Mohammed V Military Teaching Hospital, Morocco

Fri, 13 Dec 2024 00:00:00 +0000

Background: Viral gastroenteritis is a major cause of morbidity and mortality. In Morocco, epidemiological data on Norovirus remain scarce. This study aims to assess the prevalence of Norovirus and identify potential risk factors associated with infection.

Patients and Methods: From February 1 to June 13, 2024, 94 stool samples were tested for Norovirus using real-time RT-PCR. Epidemiological and clinical data were collected via a structured information sheet.

Results: The overall Norovirus infection rate was 8.5%. Most cases were among individuals aged 25-40 years, with a male-to-female ratio of 1.67. Predominant symptoms included diarrhea (100%), abdominal pain (100%), nausea (75%), fever (62%), vomiting (61.5%), and dehydration (37.5%). Key risk factors included consuming non-homemade meals (75%) and poor hygiene, such as irregular hand washing (25%).

Conclusion: This study highlights that Norovirus is a common cause of acute gastroenteritis in Morocco, highlighting the need to include other enteric viruses in the surveillance system.

Irrational Fibroma in the Central Dorsum of the Tongue: A Case Report of a Rare Location

Mon, 23 Dec 2024 00:00:00 +0000

Introduction:
Oral fibroma, also known as traumatic fibroma, irritational fibroma, or focal fibrous hyperplasia, is a benign exophytic lesion that typically arises following trauma. Fibroma is the most common benign soft-tissue neoplasm in the oral cavity.

Aim of Reporting This Case:

The aim of reporting this case is to highlight the unusual location of a traumatic fibroma on the central dorsum of the tongue.

Case Presentation:

A 55-year-old patient presented to the oral medicine clinic with a lesion on his tongue that developed after drinking a hot liquid. Clinical examination revealed a smooth, round, nodular lesion located in the central area of the dorsum of the tongue, measuring approximately 0.5 × 0.3 cm in diameter. An excisional biopsy was performed, which revealed a nodular lesion lined by papillary keratinized stratified squamous epithelium. The underlying connective tissue showed thick fibrous bundles, giant fibroblast cells, and scattered small blood vessels. So, the final diagnosis for this case was irritational fibroma.

Conclusion:
This case demonstrates an oral fibroma in an unusual location on the dorsum of the tongue following the consumption of a hot liquid. Oral fibroma is a benign neoplasm, and trauma is the most common cause. Increased awareness of this lesion is essential, as it is one of the most common benign soft-tissue neoplasms in the oral cavity.

Orofacial Granulomatosis in Upper Lip : A Case Report

Mon, 23 Dec 2024 00:00:00 +0000

Introduction:

In 1985 Wiesenfeld et al., suggest the terminology of “Orofacial granulomatosis (OFG)” to explain a chronic granulomatous lesion that involving the orofacial area include the lip, face and oral cavity, the histopathological examination usually associated with noncaseating granulomas and multinucleated Langhans‑type giant cells

Aim of Reporting This Case:

The aim of reportioning this case is highlighting the awareness of orofacial granulomatosis disease after excluding all diseases that has granulomatous lesion

Case presentation:

A 30-year-old male patient was referred to the oral medicine clinic due to swelling of the upper lip and redness of the gingiva. Clinical examination revealed a nodular lesion in the central area of the upper lip with a firm sensation upon palpation. Additionally, there was slight redness in the gingiva. The patient was medically fit, and our clinical differential diagnoses included Crohn’s disease, Wegener's granulomatosis, sarcoidosis, and orofacial granulomatosis.

Lab tests requested for the patient included CBC, ACE, ESR, and CRP. All investigations yielded negative results.The patient was also referred to internal medicine for endoscopy.A biopsy was taken from the inner area of the upper lip under local anesthesia (1.8 mL of lidocaine with epinephrine) and sent for histopathological evaluation. The histopathology report showed non-caseating granulomas, confirming the final diagnosis of orofacial granulomatosis.

Intra-lesional injection of triamcinolone acetonide (40 mg/10 mL) was initiated. At the 2-week follow-up visit, the patient reported softening of the upper lip, though the redness persisted.

Conclusion:

Swelling in the upper lip can have various potential causes, including Crohn’s disease, Wegener’s granulomatosis, sarcoidosis, and orofacial granulomatosis. Greater awareness of the oral manifestations of these conditions is essential for accurate diagnosis and effective treatment.

Effect of Implementation of Care Bundles on Emergency Abdominal Surgery Outcomes: A Systematic Review and Meta-Analysis

Thu, 19 Dec 2024 00:00:00 +0000

Background: Care bundles, comprising a set of evidence-based practices, have been widely adopted to improve patient outcomes in various clinical settings. However, their specific impact on mortality and complication rates in emergency abdominal surgical settings remains to be thoroughly quantified. Study Aim: This meta-analysis aims to evaluate the efficacy of care bundles in reducing mortality and complication rates in patients undergoing emergency abdominal surgeries. Methodology: A comprehensive literature search was conducted across PubMed, Embase, and Cochrane Library databases to identify studies evaluating the impact of care bundles on emergency abdominal surgical outcomes. Studies were included if they reported on mortality or complication rates in patients undergoing emergency surgery with and without the implementation of care bundles. Data were extracted and pooled using a fixed-effects model to calculate the overall odds ratios (ORs) and 95% confidence intervals (CIs) for mortality and complication rates. Results: Fifteen studies were included in the meta-analysis. The pooled analysis revealed a significant reduction in mortality rates in the bundle group compared to the control group, with an OR of 0.76 (95% CI: 0.68 to 0.85). Similarly, the complication rates were significantly reduced in the bundle group, with a pooled OR of 0.77 (95% CI: 0.68 to 0.89). The heterogeneity for mortality (I² = 33%) and complication rates (I² = 29%) was low, indicating consistent findings across the studies. Conclusion: The implementation of care bundles in emergency abdominal surgical settings is associated with a significant reduction in both mortality and complication rates. These findings support the broader adoption of care bundles to enhance patient outcomes in high-risk emergency surgeries. Future research should focus on conducting randomized controlled trials and evaluating the cost-effectiveness of care bundles in diverse healthcare settings.

Liver Cancer Recovery through Neo Ayurveda in 3 Months: A Case Study on the Effectiveness of Dr. SM Raju’s Standardized Treatment Protocol without Allopathic Medication

Dr. S M Raju — Thu, 26 Dec 2024 00:00:00 +0000

This study explores the potential of the Neo Ayurveda protocol, developed by Dr. S.M. Raju, in the treatment of liver dysfunction and post-cancer recovery. A 54-year-old female patient, previously treated for breast cancer (2019–2020), developed symptoms of liver dysfunction, including elevated liver enzymes and the presence of lesions, as detected by blood tests, ultrasound, and MRI in January 2023. Given her prior negative experience with chemotherapy and radiation, she opted for an alternative treatment approach through Neo Ayurveda, which integrates Ayurvedic principles with modern scientific methods, including the use of an uncooked diet ("monkey diet"), herbal supplements, and gut health optimization via prebiotics and probiotics.

The patient’s liver enzyme levels (SGOT, SGPT, Gamma GT, and Alkaline Phosphate) were monitored over the course of treatment, showing a significant reduction from elevated levels in January 2023 to normal or near-normal levels by March 2023. Specifically, SGOT reduced from 211 to 19, SGPT from 364.11 to 21, Gamma GT from 589 to 26, and Alkaline Phosphate from 310 to 108. This dramatic improvement suggests that Neo Ayurveda may play a crucial role in supporting liver recovery and overall health regeneration, even in cases of potential metastatic cancer recurrence and liver dysfunction.

The underlying mechanisms of the treatment are based on the principles of detoxification, cellular regeneration, and activation of heat shock proteins (HSP60), which are responsible for proper protein folding and organ repair. The treatment also emphasizes the importance of maintaining an alkaline body environment to support optimal organ function and prevent further disease progression.

This case study provides promising evidence for the efficacy of the Neo Ayurveda protocol in treating liver disorders and post-cancer complications, offering an alternative approach to traditional medical treatments. Further research is necessary to explore the full scope of Neo Ayurveda's potential in the management of liver diseases, cancer recovery, and other chronic conditions.