Abstract
Chylothorax is a rare condition resulting from the extravasation of chyle into the pleural space due to obstruction or injury of the thoracic duct or its tributaries. It has diverse etiologies, both traumatic and non-traumatic, and requires multidisciplinary management. We report the case of a 48-year-old patient, a chronic smoker with a 5-pack-year history, who presented with left-sided laterothoracic pain and stage II mMRC dyspnea of progressive onset for 2 months prior to admission. This revealed left-sided pleurisy with significant fluid accumulation and mediastinal adenopathy, with a reduced caliber of the left main bronchus. Flexible bronchoscopy revealed tumor-like infiltration of the left lingula and lower lobe, and bronchial biopsies were consistent with type B non-Hodgkin's lymphoma. The patient was started on chemotherapy according to the R-ACVBP protocol, with good radiological and clinical progress.