ISSN (Online): 2348-991X | ISSN (Print): 2454-9576
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Research Article
Open Access

Neutral Anesthetic Solution for Facial Aesthetic Procedures

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DOI: 10.18535/ijmsci/v12i.11.01· Pages: 7808-7813· Vol. 12, No. 11, (2025)· Published: November 28, 2025
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Abstract

Local anesthetics act selectively, paralyzing the ends and fibers of sensory nerves, thereby blocking the reception and transmission of painful stimuli. Cosmetic patients expect minimally invasive, painless, and effective procedures to enhance their appearance and boost self-confidence. Providing treatments with minimal pain and maximum patient comfort should be every professional's goal. We present the preparation of the Pithon's Neutral Anesthetic Solution (SANEP), composed of 1.2 mL lidocaine with epinephrine (2% and 1:200,000), 0.2 mL sodium bicarbonate (8.4%), and 8.6 mL sodium chloride (0.9%), for use in daily facial aesthetic procedures. We observed rapid absorption and action, resulting in less burning and pain. We also emphasize the importance of this composition because it offers excellent durability without toxic effects for patients undergoing facial aesthetic procedures. SANEP features an effective and satisfactory formulation for the clinical practice of minimally invasive procedures in the facial region.

Keywords

anesthesianerve blocklidocainesodium bicarbonateaesthetics
Author details
Gabriela Ducioni Matos
Clínica de Estética Pithon Napoli. São Paulo, SP, Brasil
✉ Corresponding Author
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João Vitor Moraes Pithon-Napoli
Clínica de Estética Pithon Napoli. São Paulo, SP, Brasil
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