Abstract
Hereby, we present a case of an elderly lady who had a previous history of chronic inflammatory disorder and was diagnosed to be suffering from systemic amyloidosis, was brought dead to the hospital with a history of fall from the bed and sudden death nesseciating an autopsy. Autopsy showed that although all the organs suffered from chronic changes, heart was particularly affected showing gross changes due to restrictive pericarditis. This case demonstrates that cardiac amyloidosis can present acutely and may be fatal. The other gross features along with the post-mortem biochemical parameters, histological changes will be discussed.