SYNTHESIS OF 6-{4-AMINO-N-[2-(DIETHYLAMINO)ETHYL]-O-ANISAMIDO-5- YL}-AMINO-2-THIO-3-SUBSTITUTEDAMINO,4-SUBSTITUTEDIMINO-1,3,5- THIADIZINES

Abstract

Recently a novel series of 6-{4-amino-N-[2-(diethylamino)ethyl]-o-anisamido-5-yl}amino-2-substitutedimino-3- substituted-4-thio-1,3,5-thiadizines was successfully synthesized by the isomerisation of 4-{4-amino-N-[2- (diethylamino)ethyl]-o-anisamido-5-yl}-amino-2,6-disubstitutedimino-1,3,5-dithiazines by 5% aqueous sodiumbicarbonate in ethanol medium. The structures of all synthesized compounds were justified on the basis of chemical characteristics, elemental analysis and spectral studies.