Comparison of glycosylated hemoglobin and different lipid parameters in with and without type-2 diabetes mellitus patients and controls

Abstract

Objective: To compare of glycosylated hemoglobin and different lipid parameters in with and without type-2 diabetes mellitus patients and controls. Methods: This was a prospective and analytical study conducted in tertiary care hospital. A total of 50 cases of diabetes with & without complication and 50 controls of either sex and 35-75 years of age were included in the study. Clinically diagnosed & confirmed cases of Diabetes Mellitus in age group 35 to 75 years with >5 years history of diabetes on treatment of any duration, patients of diabetes with complications like retinopathy, nephropathy were included in the study. Results: The FBS level was significantly (p=0.0001) higher among cases (122.26±68.39) compared with controls (79.28±11.84). The PPBS was also higher (p=0.0001) among cases (188.20±87.27) than controls (124.12±10.96). The level of HbA1C was significantly (p=0.0001) higher among cases (7.47±1.90) compared with controls (5.48±0.41). The increased level of TC, TG, LDL and VLDL was observed among cases than controls (p<0.01). However, decreased level of HDL was found among cases compared with controls (p>0.05). Conclusion: The study found that there was elevation of lipid profile and HbA1C in the patients of type-2 diabetes.