Abstract
Objective: To investigate the relationship between apparent diffusion coefficient (ADC) values and standard uptake value (SUV) in patients with non-small cell lung cancer (NSCLC).
Methods: PET/CT and diffusion-weighted magnetic resonance imaging (DW MRI) were performed in 73 consecutive patients with histologically verified NSCLC. Analysing the PET/CT data calculation of the maximum and mean SUV was performed. The mean and minimum ADC values were measured directly on the parametric ADC maps.
Results: Significant inverse correlations were found between ADCmean and SUVmean (r = - 0.53; p < 0.001) as well as ADCmin and SUVmax (r = - 0.71; p < 0.001).
Conclusions: The significant negative correlations between ADC and SUV suggest an association between tumor cellularity and metabolic activity in NSCLC.