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Articles

Rediscovering platelet number and the red cell distribution width/mean corpuscular hemoglobin ratio as markers in hemodialysis patients with iron deficiency anemia

Authors

  • Ruya Ozelsancak, MD Baskent University Faculty of Medicine Department of Nephrology Adana Medical and Research Center Dadaloglu Mah 39/6, PK: 01250 Yuregir Adana-Turkey.

Abstract

Objectives: Our aim is to evaluate the parameters of complete blood count according to transferrin saturation levels in hemodialysis patients.

Background: Iron deficiency (ID) frequently develops in patients undergoing hemodialysis (HD). It is difficult to assess the need of iron in people with chronic illness such as renal failure. Besides, there is a group of patients with high ferritin and low transferring saturation levels.

Methods: We retrospectively studied 202 subjects (F/M: 101/101) selected among 350 patients and hemoglobin concentration between 8-12 g/dL. Patients were divided into two groups according to their transferrin saturation level, <20% and ≥20% and their results were compared.

Results: The mean age of the patients and median duration of hemodialysis were not different between the groups. Levels of mean corpuscular volume (p=0.007), mean corpuscular hemoglobin (MCH; p=0.023) and lymphocytes (p=0.011) were significantly lower, and red cell distribution width (RDW; p=0.033), the RDW/MCH ratio (p=0.000), neutrophils (p=0.001), the neutrophil/lymphocyte ratio (p=0.006), leucocytes (p=0.002) and platelets (p=0.000) were higher in the transferrin saturation <20% group.

Conclusions: In the case of hemodialysis patients with high to normal serum ferritin concentrations and low transferrin saturation platelet number and the RDW/MCH ratio could assist in the diagnosis of iron deficiency anemia.

Article information

Journal

International Journal of Medical Science and Clinical Invention

Volume (Issue)

5 (9)

Pages

4043-4047

Published

2018-09-30

How to Cite

Rediscovering platelet number and the red cell distribution width/mean corpuscular hemoglobin ratio as markers in hemodialysis patients with iron deficiency anemia. (2018). International Journal of Medical Science and Clinical Invention, 5(9), 4043-4047. https://doi.org/10.18535/ijmsci/v5i9.02

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