Abstract
Hepatocellular carcinoma (HCC) is a malignant tumor derived from hepatocyte cells including primary malignant epithelial tumors. Hepatocellular carcinoma is the second most common cause of cancer-related deaths worldwide, and events are expected to increase in the future and the incidence of HCC will continue to increase until 2030. Early detection of HCC is very important to improve prognosis and long-term survival. late detection of HCC and lack of care. This study aims to determine serum AFP levels in HCC patients in DR. M. Djamil Hospital, Padang, West Sumatra, Indonesia. This research is a descriptive study, which consisted of 30 serum samples of HCC patients. The examination method is Enzyme Linked Fluorescent Assay (ELFA). In this study, the incidence of hepatocellular carcinoma in men was higher than in women. For both sexes, the incidence of HCC increases with ages between 26-60 years. The increased presence of AFP can alert doctors to the possibility of a diagnosis of HCC.