Article contents

Research Article

Effect of Different Physiological Mechanisms on Traumatic Brain Injury

Authors

  • Dr Debopriya Ghosh Senior Resident, Department Of Physiology, University College Of Medical Sciences, New Delhi.
  • Dr Ekta Verma Department of Paediatrics, All India Institute of medical Sciences, Gorakhpur, India.
  • Dr Stephen Gershman Department of Neuroscience, University of Alberta, Canada.
  • Dr Gregor Department of Chemical and Life Science Engineering, Virginia Commonwealth University, USA

Abstract

The literature has emphasised the necessity for efficient therapeutic therapies in chronic neurological disorders as TBI and other variations of chronic neurological ailments. Three common themes that cross all of these problem types have been emphasised in recent studies regarding cellular and neurochemical processes: immunological and autoimmune mechanisms, inflammatory pathways, and oxidative phosphorylation or other energy generation damage. The limitations of medical and surgical methods are clear, and they are made more difficult by the physiological interdependence of these channels. Due to the risks of polypharmacy, the prevalence of lifestyle diseases, and rising research pointing to effective treatments and procedures, there is an increasing need for non-drug, non-surgical choices. This paper reviews and links a number of studies that examine the precise, quantifiable effects of brain injury on various bodily systems, and it suggests a new direction for outcome-based, multifactorial functional neurological evaluation and treatment of some of the aftereffects of chronic TBI and mTBI (mild traumatic brain injury).

Article information

Journal

International Journal of Medical Science and Clinical Invention

Volume (Issue)

10 (01)

Pages

6381-6388

Published

2023-01-15

How to Cite

Effect of Different Physiological Mechanisms on Traumatic Brain Injury. (2023). International Journal of Medical Science and Clinical Invention, 10(01), 6381-6388. https://doi.org/10.18535/ijmsci/v10i01.04

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Keywords:

Neuroinflammation, Neurodegeneration, Neuropsychological, Neuroendocrine, Vestibular, TBI