Predictive Factors for Mortality in Adult Patients Undergoing Heart Transplantation

Abstract

Objective: To evaluate the predictive factors for mortality in adult patients undergoing heart transplantation. Method: a retrospective cohort study in a tertiary hospital, which is reference in cardiology and pneumology in Latin America. It was included 70 patients older than 18 years who underwent heart transplantation and excluded patients under 18 years as well as those diagnosed with congenital heart disease. Results: No differences were observed between the groups in relation to male gender (67.2% vs. 66.7%, p=0.969) and age (44 + 12 vs. 52 + 13, p=0.086). Regarding comorbidities the groups were not different, however, when comparing the score values of the Cleveland Clinic we observed a significant difference (5 [4 – 7] vs. 7 [5.25 – 8.75], p=0.010), being higher in the nonsurvivors group. In the multivariate analysis we observed that the Cleveland Clinic Score (OR: 1.573, p=0.007), baseline creatinine greater than 1.5 mg / dL (OR: 3.426, p=0.007), previous cardiac surgery (OR: 5.200, p = 0.032) and need for dialysis (OR: 6.750, p = 0.017) were the main predictive factors for death. Conclusion: The main predictive factors for death in this population were Cleveland Clinic Score increased, baseline creatinine greater than 1.5 mg / dL, having undergone heart surgery in advance and requiring dialysis. Descriptors: Heart Transplantation; Mortality; Thoracic Surgery; Postoperative Complications.