Effect of Type 2 Diabetes Mellitus on Cognitive function and EEG in elderly patients

Abstract

Introduction: Diabetes is a major health problem in India, Type 2 is also the most common type seen. Diabetes is associated with cognitive decline in elderly patients. Hyperglycemia, age, sex and duration of diabetes mellitus all seems to affect cognitive function.

Objectives: Aim of the study is to assess the EEG changes and cognitive function in elderly type 2 diabetes mellitus patients.

Materials and methods: Two groups of people, 20 in each group who are age sex matched were selected and case group of elderly diabetic patients and control group of healthy subjects were selected. EEG recordings were done using MP36 – BIOPAC 4 channel instrument and cognitive function was assessed using MMSE.

Results: The elderly diabetic group was having declined cognitive function – MCI (Mild Cognitive Impairment) and reduced EEG wave activity.

Conclusion: Reduced EEG alpha wave activity is seen in elderly diabetic patients. Reduced functional connections in cortex and hyperglycemia induced pathologic changes could be the causative factors.