The prediction of Prostate Cancer Based on Normal Digital Rectal Examination and Normal Prostate Specific Antigen in Clinical Benign Prostate Hyperplasia

Abstract

Purpose: To evaluate the prediction of prostate cancer based on normal digital examination (DRE) and normal prostate specific antigen (PSA) in clinical Benign Prostate Hyperplasia.

Materials and Methods: We reviewed medical records of prostate cancer in prostate enlargement patients with urinary retension underwent transurethral resection of the prostate  (TURP) based on  normal DRE, and normal PSA in Arifin Achmad Regional General Hospital, Pekanbaru, Riau Province, Indonesia in January 2010 – Desember 2016. Statistical analysis of univariate was used. Approval on the study was obtained from the Ethical Review Board for Medicine and Health Research, Medical Faculty, University of Riau.

Results: There were 644 prostate enlargement patients with urinary retension underwent TURP) in this study in which mostly (51%) in 60-69 year age group,  Most (69.7%) DRE were normal and PSA levels of ≤ 4 ng/ml  were in 122 (19%) patients. There were 19 (18.5%) prostate cancer in patients with normal DRE and PSA.

Conclusion: We found there were 19 (18.5%) prostate cancers in prostate enlargement patients with normal DRE and PSA findings as the prediction.