Abstract
Langerhans cell Histiocytosis (LCH) is a rare disease affecting predominantly children.A case of LCH may involve single organ, single system or it may involve single site (unifocal),multiple site, multifocal or it may involve multiple organ(multisystem). Here a case of multifocal LCH in a two and half year old child is presented where FNAC was helpful in achieving a rapid and accurate diagnosis in an appropriate clinical and radiological setting.This can avoid unnecessary biopsy and guide the management especially when patient is very sick and doesnot give concent for biopsy . The highly characteristic common and rare cytological features are highlighted with focus on differential diagnosis