Antibiotic Susceptibility Pattern of Bacterial Uropathogens Causing Urinary Tract Infection

Abstract

Introduction: Urinary tract infections (UTIs) are the commonest infections in man mainly caused by Escherichia coli and other different members of family Enterobacteriacae. Enterococci and coagulase negative Staphylococci are important gram positive bacteria.Uncontrolled antibiotic usage has contributed to the worldwide emergence of resistant strains.Objectives: Assess responsible uropathogens and evaluate their antibiotic susceptibility pattern to the commonly used antimicrobial agents.Methods: The study was performed on UTI cases from January 2016 to June 2016. 1216 (708 females and 568 males) urine samples were analyzed. Antibiotic susceptibility testing (AST) was read according to Clinical Laboratory Standards Institute (CLSI) guide lines.Results: Culture positive bacteriuria was detected in 154 cases (12.66%) — 96 isolates were E. coli. All the bacterial isolates showed high levels of antimicrobial resistances against the commonly prescribed drugs; least resistance for drugs such as Meropenem and Cefepine.Conclusion: Routine surveillance and monitoring studies should be conducted for the most effective empirical treatment of UTI.