Abstract
Bystander haemolysis is a devastating consequence of delayed haemolytic transfusion reaction (DHTR) in cases of sickle cell disease receiving multiple transfusions. This can be potentially a life-threatening complication, which should be kept in mind while treating patients of sickle cell disease with haemolytic crisis. We present a case of a 22-year-old male who presented to us with symptoms of severe anaemia; later, diagnosed as DHTR and managed accordingly.