Abstract

Introduction. Cardiopulmonary bypass (CPB) is widely used to regulate systemic perfusion and oxygenation during open heart surgery. During the use of CPB machines may be at risk of disrupting tissue perfusion and also after surgery is undertaken. The increase of lactic acid is a metabolic characteristic that results from the consequences of hypoxia, but this increase in lactic acid may also occur by a condition not caused by hypoxia. The purpose of this study was to investigate the relationship between CBP use and elevated lactic acid levels in patients with open heart surgery at RSUP H. Adam Malik Medan. Methods. This study used a design of correlative test research with retrospective approach.. The implementation of the study was conducted in the Division of Cardiothoracic and Vascular Surgery, Department of Surgery, Faculty of Medicine USU/ RSUP H. Adam Malik Medan. We studied patients undergoing open cardiopulmonary surgery using the Cardiopulmonary Bypass (CBP) at RSUP H. Adam Malik Medan in 2016, the data of CPB use and lactic acid values that met the inclusion criteria. Results. The number of research subjects was 30 people. Based on the results of the above study, any addition of CPB time more than 1 minute it will affect the increase in lactic acid 0.131 mg. The correlation between the duration of CPB and Lactic acid concentration with a large R value is 0.743. This indicated that there was a correlation between the duration of CPB and lactic acid concentration. Conclusion. Bivariatally there was a relationship between duration of CPB use and elevated lactic acid levels in patients with open heart surgery with r = 0.743. In this investigation there were several confounding factors controlled by patient selection and the same surgical technique.

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