Abstract

Background: At every stage of chronic kidney disease, cardiovascular disease leads as the predominant cause of morbidity and mortality. There is a 10 – 200 fold increased risk for cardiovascular disease in patients with CKD in comparison to general population. Aim: To study the various cardiac abnormalities in chronic kidney disease and correlate clinical presentation with echocardiographic findings. Materials and Methods: This cross sectional study was conducted in Aarupadai Veedu Medical College and Hospital, Puducherry from February 2017 to july 2017. All adult chronic kidney disease patients of both sexes were included in the study after obtaining informed consent. A detailed history taking and a thorough physical examination was performed followed by investigations including echocardiography. Cardiac abnormalities were studied and these were correlated to echocardiographic findings. SPSS software was used for statistical purposes. Results: A total of 50 cases of chronic kidney disease were included in the study. 33 patients were males and 17 patients were female. Mean age of patients studied was 55.16 ± 10.71. Hypertension was found in 41 of 50 patients. Of these, 27 patients had concentric left ventricular hypertrophy. 20 of 50 patients had coronary artery disease . Ischemic dilated cardiomyopathy was observed in 12 of these 20 patients. 22 of 50 patients were having heart failure. Pericardial effusion was seen in 16 patients. Atrial fibrillation was present in 6 of 50 patients. CONCLUSION: Cardiac abnormalities are common in chronic kidney disease. Hypertensive heart disease is the commonest clinical manifestation in patients with chronic kidney disease. Heart failure, coronary artery disease and pericardial effusion are other common manifestations. Concentric left ventricular hypertyrophy and Ischemic dilated cardiomyopathy are associated with declining glomerular filtration rate.