Abstract

Background – Aim of this study is to evaluate cytomorphological pattern and thyroid hormone profile analysis which provides information about physiological and pathological condition and help in the early detection of various thyroid diseases and there by reduces surgical intervention . Objectives – 1.To obtain the results of fine needle aspiration cytology (FNAC) and thyroid hormone profile in diagnosis of different benign lesions and neoplastic lesions. 2. confirmation of clinically diagnosed neoplastic lesions. Materials and Method – During the study period June 2013 to May 2014 Fine needle aspiration cytology (FNAC) was performed on 198 patients with clinical history of thyroid diseases Thyroid function test also performed whenever possible. Results –One ninety eight cases both males and females were analysed. Analysis of thyroid hormone profile was possible in 147 cases, age range in this study was 1-80 years. Most commonly affected age group was 3rd to 4th decades.There were 171 (86.36%)females and 27(13.64%) males.Most commonly encountered lesion was colloid goiter accounting for 101 cases. There were 188 non neoplastic lesions and 10 cases were found to be neoplastic.Maximum number of patients, 99 cases were euthyroid followed by hyperthyroid (22 cases) and hypothyroid (19 cases). Conclusion – Fine needle aspiration cytology (FNAC) and thyroid hormone profile are highly effective procedure for the assessment of patients with thyroid lesions. All type of thyroid lesions must be analysed in the light of clinical picture , FNAC and thyroid hormone profile to minimize the risk of false negative report. Early and accurate diagnosis of different thyroid lesions minimize surgical intervention and there by morbidity and mortality.