Serous Atrophy Of The Marrow In Anorexia Nervosa – A Case Report

Abstract

Anorexia nervosa is a psychiatric disorder characterized by a purposeful dietery restrictionand altered alimentary habits,with very few cases having been reported from India. Hematologic manifestations include cytopenias.Bone marrow aspirations usually yield a dry tap probably due to serous degeneration and biopsy usually reveals alterations in bone marrow adipocytes with deposition of pink homogeneous material. Serous atrophy of bone marrow is a rare disorder characterized by fat cell atrophy, loss of hematopoietic tissueand deposition of extracellular matrix by mucopolysaccaharides. It has been described ina variety of chronic diseases like cancer-related cachexia, anorexia nervosa due to starving, infections, and malignant neoplasms, including lymphoma.We hereby present a case of 50 year old woman who presented with fatigue and loss of appetite since a yearalong with bilateral pedal edema and breathlessness