Abstract
Uterine leiomyomas represent the most common benign tumors of the female reproductive tract. Giant uterine leiomyomas are very rare neoplasms and represents a great diagnosis and therapeutic challenge. This article illustrates a case of a 40-year old woman presented to our surgery department with a 6-month history of progressive increasing abdominal size, back pain, vague abdominal pressure sensations, weight loss, constipation and urinary frequency. Physical examination, laboratory evaluation, trans-abdominal ultrasound and computed tomography scanning suggested a giant abdomino-pelvic mass. Abdominal supracervical hysterectomy with bilateral salpingo-oophorectomy was performed. Histologically, the specimen was a 20 Kg uterine leiomyoma measuring 33/28/22 cm. The patient’s postoperative evolution was uneventful and she was discharged from the hospital on the tenth postoperative day.