Abstract
Background: Collagen vascular diseases are a heterogenous group of autoimmune disorders of unknown etiology of which ILD is the most common pulmonary complication. Treatment is usually aimed at slowing or preventing progression rather than in the hope of a striking short-term response.
Materials and Methods: The aim of the study is to assess response to treatment in patients with collagen vascular disease associated Interstitial lung disease who were started on combination of Azathioprine and Prednisolone.
Results: Majority of patients remained stable following 6 months of treatment.
Improvement in FVC in millilitres showed a trend towards significant difference between UIP and NSIP patterns of ILD.
Conclusion:Treatment response in collagen vascular disease associated ILD is largely dependent on the type of underlying lung disease.