Carcinoma Cervix With Brain Metastasis: Report Of Two Cases And Review Of Literature

Abstract

Brain metastasis from carcinoma cervix is a rare clinical entity. Incidence of brain metastasis in carcinoma cervix ranges from 0.5-1.2 %. Cervical cancer usually spread by local extension and through the lymphatic to the retroperitoneal lymph node. Distant hematogenous spread to the brain is an uncommon and late event with poor prognosis. Herein we are reporting two cases of advanced carcinoma cervix that developed brain metastasis after two years of completion of treatment. Both cases were treated with whole brain radiotherapy. One of them responded well to treatment and was disease free at 11 months follow up and another patient died 3 months after completion of treatment. This case being reported due to rarity of brain metastasis in carcinoma cervix