Abstract

INTRODUCTION Neonatal sepsis is a clinical syndrome characterized by systemic signs of infection and accompanied by bacteremia in the first month of life. Neonatal sepsis is among the three most common illness in the newborn and is second most common cause of mortality among preterm and low birth weight babies. AIMS AND OBJECTIVES PRIMARY1) To predict the sepsis on the basis of clinical features. 2) To assess variability of sepsis among preterm and term babies admitted in NICU. SECONDARY3) To study agent causing sepsis and antibiotic sensitivity pattern of isolates. MATERIAL AND METHODS The Present Descriptive prospective study was conducted in Neonatal intensive care unit, Department of paediatrics, Subharti Medical College, Meerut from june 2014 to june 2015 on 150 neonates (term and preterm) admitted with feature suggestive of sepsis. All neonates included in our study were examined in detail with sepsis screening including blood culture as gold standard and other relevant investigation were carried out. OBSERVATION AND RESULTS A total of 150 neonates were registered for the study out of which sepsis was noted to be higher in males 94(62.67%) as compared to females 56 (37.33%). The male to female ratio was 1.6:1. 35(23.33%) of babies with sepsis were very low birth weight babies, (46.66%) of babies were low birth weight and 45 (30%) of babies had weight >2500grams. 111(74%) babies with sepsis were born by vaginal route while 39(26%) were delivered by caesarean section with almost 3:1. Early onset sepsis was present in 61 (40%) and 89(60%) had late onset sepsis.