Abstract
With detection by cytological test, the incidence of cervical cancer was reduced more than 50%; the cause of this cancer are high risk human papilloma viruses; required a sensitive test that provide sensitivity and specificity sufficient for this cancer, not to develop increasing screening intervals when the results are negative. High risk human papilloma virus testing, is safe and effective because of their excellent sensitivity and negative predictive value together with an optimum reproducibility, mainly when combined with cytology based liquid with biomarkers and viral load, will have greater sensitivity and specificity, and reduction of false positives for the detection of cervical intraepithelial neoplasia grade 2 or more and excellent clinical benefit for cancer detection cervical and other related diseases with the infection of the the human papilloma virus, such as the detection of anal intraepithelial neoplasia and cancer anal in high risk groups; He is currently the best tool for early detection of HPV infection and the risk of carcinogenesis.