ISSN (Online): 2348-991X | ISSN (Print): 2454-9576
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Assessment of Burn Wound Healing Property of Ocimum sanctum by Grading of Epithelial Regeneration in Rabbits

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DOI: 10.18535/ijmsci/v5i6.03· Pages: 3865-3867· Vol. 5, No. 6, (2018)· Published: June 30, 2018
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Abstract

Burns remain a major public health problem all over the world, especially in developing countries. Pseudomonas aeruginosa is a major cause of infection and a contributing factor in the death of patients with burns. So, there is a growing need to develop drugs which will prevent infections and complications more effectively than the presently used drugs. Ocimum sanctum L. (Holy basil in English and Tulsi in Hindi) has been shown to have antioxidant, antimicrobial, anti-inflammatory and wound healing properties. The present study was carried out to evaluate the epithelial regeneration property of Ocimum sanctum in thermal burns with and without supportive treatment of Ointment Silver Sulfadiazine. After the end of treatment at 28th day, group treated with Ointment Silver sulfadiazine + Ocimum sanctum showed significant epithelial generation (p-value 0.02, p<0.05 Significant).

Author details
Vaibhav Kumar Gupta
✉ Corresponding Author
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Vaibhav Kumar Gupta
Assistant Professor, Department of Pharmacology, Shri Shankaracharya Institute of Medical Sciences, Bhilai-490020, Chhattisgarh, India
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Akhilesh Kumar
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Akhilesh Kumar
Associate Professor, Department of Pharmacology, Chirayu Medical College and Hospital, Bhopal-462030, Madhya Pradesh, India
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