Abstract

INTRODUCTION: Hypothyroidism is a common disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormone AIMS AND OBJECTIVES: To study aetiology, epidemiological parameters and clinical profile of hypothyroidism in children up to 12 years of age presenting at tertiary care hospital. DESIGN OF STUDY: Prospective Analytic study done at Department of Paediatrics, B J Medical College, Ahmedabad From 1st September 2015 To 31st August 2016. RESULTS: In this study the thyroid dysfunction has a peak in infancy. Hypothyroidism is more common in females (62%) as compares to male (38%) and male:female ratio is 1:1.6. Out of 55 cases 32.7% were under nutrition, 12.7% had over weight and 54.5% had normal weight and stunting found in 17(30.9%) cases. Lethargy(63%) being more common symptoms followed by developmental delay(55%). Non pitting oedema (47%) was most common sign followed by delayed closure of anterior fontanelle. Congenital hypothyroidism (62%) being most common type. The mean T3, T4 and TSH levels in our study of hypothyroids was 38.06 µg/ dl, 2.72µg/dl and 62.4µu/ml respectively. On thyroid scan thyromegaly is most common observed (33.3%). CONCLUSION: From this study we can find the current scenario of hypothyroidism in paediatrics patients and find that the congenital hypothyroidism is the most common cause which present in early infancy. By early diagnosis and treatment, we can give a better life to our patient.

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